A. According to the mode of dispersion:
1. O/W (Oil in Water):
- Oil is an internal phase
- Water is an external phase
- e,g.yolk, Vanishing cream
2. W/O (Water in oil):
- Water is an Internal Phase.
- Oil is an External Phase.
- e,g. cold cream,
3. Multiple phases emulsion:
- W/O/W
-o/w/o
B. In case of consistency-
a) Liquid emulsion:
- usually o/w type
- used parenterally, orally & externally
b) Semisolid emulsion:
- o/w or w/o type
- usually used for external purposes.
C.In accordance to particle size-
· Coarse emulsion:
globule size greater than 5μm
· Fine emulsion:
below 5μm
· Microemulsion:
< 120nm
don’t refract light
transperant appearance
D. According to our route of administration
a) Emulsion for internal use:
- oral, IV
b) Emulsion for external use:
- liniment & lotion
E. According to HLB value
a) Hydrophilic:
- o/w type
- HLB value of the water phase 9-18
b) Lipophilic:
- w/o type
- HLB value of the oil phase 3-8
DIFFERENCE BETWEEN O/W AND W/O EMULSIONS
O/W | W/O |
Here water is as a dispersion medium and oil is the dispersed phase | Here Oil is as a dispersion medium besides water is the dispersed phase |
They are non greasy, removable from the skin surface | They are not water removable & greasy in nature. |
Used externally to deliver cooling effect e.g. vanishing cream | Used externally to stop evaporation of moisture from the skin surface e.g. Cold cream |
Water soluble drugs are actually released more quickly from o/w emulsions | Oil soluble drugs are more quickly released from w/o emulsions |
bitter taste of oils can be masked. So these kind of dosage forms are preferred by consumer & manufacturer. | They are preferred for formulations meant for external use like creams. |
O/W emulsions give a positive conductivity test . | W/O emulsions do not give a positive conductivity.. |
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